BDBM50501885 CHEMBL4441173::US10807974, Example 68::US10995088, Example 68::US11608330, Example 68

SMILES CS(=O)(=O)c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)-c1ccccc1

InChI Key InChIKey=ADIBEGOVRYXDOX-UHFFFAOYSA-N

Data  26 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50501885   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50: >1.00E+5nMAssay Description:Promega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821Inhibitors (Test compounds):10 mM stock diluted to 10, 3, 1, 0.3, 0.1, 0.03, 0.01, 0.003, 0.001, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-B Enzyme: Sigma, Cat No. M7441.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50: >1.00E+5nMAssay Description:The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cells using MAO substrate measured after 1 hr by luciferin reagent-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed